解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Comprehensive long-term studies of isolated populations provide valuable comparative data that may be used to evaluate different methods for quantifying the relationship between genetic diversity and fitness. Here, we report on data collected from large and well-characterized cohorts of the two numerically dominant sp...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800409
更新日期:2004-04-01 00:00:00
abstract::Understanding the breeding system and population genetic structure of invasive weed species is important for biocontrol, and contributes to our understanding of the evolutionary processes associated with invasions. Hieracium lepidulum is an invasive weed in New Zealand, colonising a diverse range of habitats including...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800392
更新日期:2004-03-01 00:00:00
abstract::Patterns of pollen dispersal are central to both the ecology and evolution of plant populations. However, the mechanisms controlling either the dispersal process itself or our estimation of that process may be influenced by site-specific factors such as local forest structure and nonuniform adult genetic structure. He...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800397
更新日期:2004-03-01 00:00:00
abstract::A general prediction of the neutral theory of evolution is that genetic diversity should correlate positively with effective population size. We show here that diversity across eight microsatellite loci was consistently and substantially lower in one common amphibian (Bufo bufo) than in another with similar life histo...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800391
更新日期:2004-02-01 00:00:00
abstract::Pedunculate oak and sessile oak are two sympatric interfertile species that exhibit leaf morphological differences. We aimed to detect quantitative trait loci (QTLs) of these traits in order to locate genomic regions involved in species differentiation. A total of 15 leaf morphological traits were assessed in a mixed ...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800358
更新日期:2004-01-01 00:00:00
abstract::Dispersal in most plants is mediated by the movement of seeds and pollen, which move genes across the landscape differently. Grevillea macleayana is a rare, fire-dependent Australian shrub with large seeds lacking adaptations for dispersal; yet it produces inflorescences adapted to pollination by highly mobile vertebr...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800308
更新日期:2003-11-01 00:00:00
abstract::Blue mussels of the genus Mytilus have an unusual mode of mitochondrial DNA inheritance termed doubly uniparental inheritance (DUI). Females are homoplasmic for the F mitotype which is inherited maternally, whereas males are heteroplasmic for this and the paternally inherited M mitotype. In areas where species distrib...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800345
更新日期:2003-10-01 00:00:00
abstract::Parasitic wasps (parasitoids) use volatiles from the plants infested by phytophagous insects to locate host herbivores, but their behavioural response to such semiochemicals is highly variable. Bi-directional selection on Cotesia glomerata (Hymenoptera: Braconidae) was conducted to investigate the importance of geneti...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800340
更新日期:2003-10-01 00:00:00
abstract::Wolbachia are a group of maternally inherited bacteria that infect a wide range of arthropods. Wolbachia infections are known to result in the expression of various abnormal reproductive phenotypes, the best known being cytoplasmic incompatibility. The first systematic survey of 42 spider mite species in Japan reveale...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800329
更新日期:2003-09-01 00:00:00
abstract::Using fast-evolving microsatellites, more slowly evolving ITS markers and performing habitat analyses, we demonstrated a drastic genetic divergence and significant habitat differentiation between early- and late-flowering variants of plants morphologically belonging to Gymnadenia conopsea ssp conopsea. The two phenolo...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800334
更新日期:2003-09-01 00:00:00
abstract::Stable hybrid zones in which ecologically divergent taxa give rise to a range of recombinants are natural laboratories in which the genetic basis of adaptation and reproductive isolation can be unraveled. One such hybrid zone is formed by the fire-bellied toads Bombina bombina and B. variegata (Anura: Discoglossidae)....
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800291
更新日期:2003-08-01 00:00:00
abstract::The interaction between rapidly evolving centromere sequences and conserved kinetochore machinery appears to be mediated by centromere-binding proteins. A recent theory proposes that the independent evolution of centromere-binding proteins in isolated populations may be a universal cause of speciation among eukaryotes...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800275
更新日期:2003-07-01 00:00:00
abstract::Local patterns of genetic variation were analysed in the land snail Helix aspersa for 32 populations sampled within a patchy agricultural landscape: the polders of the Bay of Mont-Saint-Michel (France). This investigation examined the allele frequencies at four enzymatic markers and five microsatellite loci through th...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800256
更新日期:2003-06-01 00:00:00
abstract::Knowledge of the mechanism underlying the expression of melanin-based sex-traits may help us to understand their signalling function. Potential sources of inter-individual variation are the total amount of melanins produced but also how biochemical precursors are allocated into the eumelanin and phaeomelanin pigments ...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800260
更新日期:2003-05-01 00:00:00
abstract::It was shown previously that the long lifespan and juvenile phase of trees strongly attenuate founder effects during colonisation in a diffusive dispersal model. However, this model yielded too slow a colonisation rate in comparison with palynological data for temperate forest trees. Since rare long-distance dispersal...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800243
更新日期:2003-04-01 00:00:00
abstract::In the solitary parasitoid wasp Venturia canescens both arrhenotokously (sexual) and thelytokously (parthenogenetical) reproducing individuals occur sympatrically. We found in the laboratory that thelytokous wasps are able to mate, receive and use sperm of arrhenotokous males. Using nuclear (amplified fragment length ...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800245
更新日期:2003-03-01 00:00:00
abstract::The phytophagous insects that damage crops are often polyphagous, feeding on several types of crop and on weeds. The refuges constituted by noncrop host plants may be useful in managing the evolution in pest species of resistance to the Bacillus thuringiensis toxins produced by transgenic crops. However, the benefits ...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800186
更新日期:2003-02-01 00:00:00
abstract::Hybridization between wild and domestic bovine species occurs worldwide either spontaneously or by organized crossing. We have analysed hybridization of banteng (Bos javanicus) and zebu (Bos indicus) in south-east Asian cattle using mitochondrial DNA (PCR-RFLP and sequencing), AFLP, satellite fragment length polymorph...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800174
更新日期:2003-01-01 00:00:00
abstract::Variations observed in parasite virulence and host resistance may be the outcome of coevolutionary processes. Recent theoretical developments have led to a 'geographic mosaic theory' of coevolution according to which there are some localities where reciprocal selection occurs (hot spots) and others where it is strongl...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800182
更新日期:2003-01-01 00:00:00
abstract::Matrilineal phylogenetic divergence among Atlantic salmon stocks of the Bay of Fundy in south eastern Canada is investigated. Sequence variation in two regions of the mitochondrial ND1 gene, encompassing 710 base pairs, is described for 168 salmon from 11 rivers. Mean overall haplotype and nucleotide diversity (h and ...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800166
更新日期:2002-12-01 00:00:00
abstract::We review and discuss the importance of correlational selection (selection for optimal character combinations) in natural populations. If two or more traits subject to multivariate selection are heritable, correlational selection builds favourable genetic correlations through the formation of linkage disequilibrium at...
journal_title:Heredity
pub_type: 杂志文章,评审
doi:10.1038/sj.hdy.6800148
更新日期:2002-11-01 00:00:00
abstract::Here I develop the idea that ubiquitous harmful genome-wide mutation with local differentiation favors dispersal, even though migration reduces average fitness. Historical contingency of the mutational process means that demes (sub-populations) differentiate from one another. Deleterious or lethal partially recessive ...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800143
更新日期:2002-10-01 00:00:00
abstract::F-statistics were employed to analyse quantitative and allozyme variation among 19 native populations of maritime pine (Pinus pinaster Ait.). Fourteen polymorphic allozyme loci were used to provide an empirical basis for constructing a null hypothesis to test natural selection as a determinant of quantitative evolutio...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800114
更新日期:2002-09-01 00:00:00
abstract::Two hundred and thirty-six mitochondrial DNA nucleotide sequences were used in combination with polymorphism at four nuclear microsatellite loci to assess the amount and distribution of genetic variation within and between African savannah elephants. They were sampled from 11 localities in eastern, western and souther...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800110
更新日期:2002-08-01 00:00:00
abstract::A total of 76 sweet cherry genotypes were screened with 34 microsatellite primer pairs previously developed in peach. Amplification of SSR loci was obtained for 24 of the microsatellite primer pairs, and 14 of them produced polymorphic amplification patterns. On the basis of polymorphism and quality of amplification, ...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800101
更新日期:2002-07-01 00:00:00
abstract::We investigate the effects of consanguinity and population substructure on genetic health using the UK Asian population as an example. We review and expand upon previous treatments dealing with the deleterious effects of consanguinity on recessive disorders and consider how other factors, such as population substructu...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800090
更新日期:2002-06-01 00:00:00
abstract::Seven different mildew resistant wheat lines derived from crosses between triticale and bread wheat were examined by molecular cytogenetics and chromosome C-banding in order to determine their chromosomal composition. Genomic in situ hybridisation (GISH) showed the presence of rye germplasm in all the lines and identi...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800051
更新日期:2002-05-01 00:00:00
abstract::Araucaria araucana (Monkey Puzzle), a southern South American tree species of exceptional cultural and economic importance, is of conservation concern owing to extensive historical clearance and current human pressures. Random amplified polymorphic DNA (RAPD) markers were used to characterise genetic heterogeneity wit...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800033
更新日期:2002-04-01 00:00:00
abstract::Fluctuating asymmetry (FA) has been proposed as a tool to measure levels of stress experienced by populations of organisms during development. To be of value as a bio-marker to highlight conditions at particular sites, it is important that variation in FA is due to environmental (eg pollution) variation and not geneti...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800045
更新日期:2002-04-01 00:00:00
abstract::The vertical transmission of Wolbachia in two species of spider mite was investigated and compared. One species, Tetranychus kanzawai Kishida, was infected with a modification negative strain of Wolbachia while the other species, Panonychus mori Yokoyama, was infected with a modification positive strain. The infection...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800026
更新日期:2002-03-01 00:00:00
abstract::Sex ratio theory attempts to explain variation at all levels (species, population, individual, brood) in the proportion of offspring that are male (the sex ratio). In many cases this work has been extremely successful, providing qualitative and even quantitative explanations of sex ratio variation. However, this is no...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800018
更新日期:2002-02-01 00:00:00
abstract::The frequency of individuals resistant to two acetolactate synthase (ALS)-inhibiting herbicides in three previously untreated populations of Lolium rigidum was determined. The frequency of individuals resistant to the sulfonylurea herbicide sulfometuron-methyl varied from 2.2 x 10(-5) to 1.2 x 10(-4) and the frequency...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800004
更新日期:2002-01-01 00:00:00
abstract::A conspicuous shell polychromatism is observed in colonies of Cepaea nemoralis from western France (Brittany). The present study is intended to search for a spatial structure of shell features at this scale and to infer evolutionary processes from the observed patterns. We used a database of morph frequencies (six com...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800012
更新日期:2002-01-01 00:00:00
abstract::Gene flow was investigated in Anopheles gambiae from eight localities that span the ecological zones of Nigeria (arid savanna zones in the north gradually turn into humid forest zones in the south). Genetic differentiation was measured over 10 microsatellite loci and, to determine any effects of selection, five loci w...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1046/j.1365-2540.2001.00957.x
更新日期:2001-12-01 00:00:00
abstract::The genetic control of self-incompatibility (SI) was studied in the Mediterranean short-lived perennial species Anagallis monelli (Primulaceae: Myrsinaceae). Arrays of siblings, including families derived from reciprocal crosses, were cross-pollinated in full diallels, and compatibility groups were assesssed from a ce...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1046/j.1365-2540.2001.00951.x
更新日期:2001-11-01 00:00:00
abstract::Porcellionides pruinosus is a cosmopolitan woodlouse. It is known to exhibit patterns of geographical variation between populations, and has been suspected to consist of several very closely related species. This species was found to carry Wolbachia endosymbionts, alpha-proteobacteria which are known to modify the rep...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1046/j.1365-2540.2001.00920.x
更新日期:2001-10-01 00:00:00
abstract::Geographical range is considered a good predictor of the levels of isozyme variation in plants. Widespread species, often consisting of historically larger and more continuous populations, maintain higher polymorphism and are less affected by drift, which tends to erode genetic variation in more geographically restric...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1046/j.1365-2540.2001.00906.x
更新日期:2001-09-01 00:00:00
abstract::In order to extend present knowledge of brown trout phylogeography in the Palaearctic, we analysed the complete mitochondrial D-loop sequence (1025-1027 bp) of all mitochondrial haplotypes of Salmo trutta found in the Iberian Peninsula and one North African haplotype. Sequence variation in the mitochondrial control re...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1046/j.1365-2540.2001.00905.x
更新日期:2001-08-01 00:00:00
abstract::Random amplified polymorphic DNA (RAPD) analysis was performed to characterize the genetic diversity of Austropotamobius pallipes, a threatened freshwater crayfish native to Europe. Four decamer primers which generated six unambiguous polymorphic bands were used to analyse crayfish from 21 populations sampled in the m...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1046/j.1365-2540.2001.00909.x
更新日期:2001-07-01 00:00:00
abstract::Hybridization between crops and their weedy or wild relatives is an area of concern because the widespread use of genetically engineered crops may allow novel, beneficial transgenes to enter nearby populations. We compared fitness components of wild Cucurbita pepo from Arkansas, USA, with wild-crop hybrids derived fro...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1046/j.1365-2540.2001.00890.x
更新日期:2001-06-01 00:00:00